US Highways Route - US 2 [I]
| Route | From | To | Miles | States passed through | Replaced by | Notes |
| US 2 [I] | Houlton, ME * | Rouses Point, NY (*) | 460 (461) | ME NH VT NY | US 3 VT-102 US 5 US 302 US 11 | Since 1926; E Leg; W exten 1930 |
| US 2 [II] | (Sault Ste. Marie, MI *) St Ignace, MI | Everett, WA | 2119 (2200) | MI WI MI WI MN ND MT ID WA | MI-129 MI-134 I-75 WI-77 US 51 WI-137 (US 2S) | Since 1926; /N//S/ W Leg; Exten W 1948; E trunc 1984 |
| (US 102) | (Crystal Falls, MI) | (Covington, MI +) | (36) | (MI) | US 141 | Exist 1926-1928, First US route decommissioned |
| US 202 | Bangor, ME | Basin Corner, DE | 627 (647) | ME NH MA CT NY NJ PA DE | Alt US 1 Alt US 202 NH-202A MA-2A NJ-179 PA-179 | Since 1934; Original south end State Road, DE; South trunacted at Farnhurst, DE 1964; Extended south 1984 |
| US 302 | Portland, ME | Montpelier, VT | 171 | ME NH VT | Nill | Since 1935 |
| US 4 | Portsmouth, NH | E. Greenbush, NY | 256 | NH VT NY | NH-16 NH-9 US 202 US 3 NH-11 NY-254 | Since 1926; W exten 1930 |
| (US 104) | (Maple View, NY) | (Niagara Falls, NY *) | (167) | (NY) | NY-104 NY-404 CR-103 NY-104 | Exist 1934-1971; Never connected to US 4 |
| US 6 | Provincetown, MA | Bishop, CA (Long Beach, CA) | 3205 (3652) | MA RI CT NY PA OH IN IL IA NE CO UT NV CA | CT-66 CT-31 CT-11 CT-4 CT-10 CT-72 US 6N [I] US 209 US 15 PA-660 PA-155 PA-46 PA-97 US 6N [II] US 19 I-80 IA-927 IA-90 IA-925 CA-1 I-110 CA-110 I-5 CA-14 US 395 | Since 1926; /N//N//N/ E + W sects cntcd 1928; W Exten Greeley, CO 1931; W trunc Wiggins, CO 1937; W exten Long Beach, CA 1937; Paving complete 1952; Trunc 1964; Also known as The Grand Army of the Republic Highway |
| (US 106) | (Narrowsburg, NY -) | (Wyalusing, PA) | (95) | (NY) (PA) | CR-24 PA-652 US 6 PA-106 US 11 PA-706 | Exist 1926-1973; May not have entered NY |
| US 206 | Milford, PA | Hammonton, NJ | 131 | PA NJ | NJ-183 | Since 1934 |
| US 8 | (Powers, MI) Norway, MI | Forest Lake, MN (Minneapolis, MN) | 281 (312) | MI WI MN | US 2 US 61 I-35W | Since 1926; E trunc Pembine, WI 1928; E exten 1928; W trunc 1980 |
| (US 208) | (Carlton, MN) | (Motley, MN) | (127) | (MN) | US 210 MN-210 | Shown on maps in 1934 |
U.S. Highways
| US 1 | US 11 | US 21 | US 31 | US 41 |
| US 51 | US 61 | US 71 | US 81 | US 91 |
| US 2[I] | US 10 [I] | US 20 [I] | US 30 | US 40 |
| US 50 | US 60 | US 70 | US 80 | US 90 |